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You need to upgrade your Flash Player| A. New York Heart Association functional classification | |
| Class 1: | No symptoms with ordinary physical activity. |
| Class 2: | Symptoms with ordinary activity. Slight limitation of activity. |
| Class 3: | Symptoms with less than ordinary activity. Marked limitation of activity. |
| Class 4: | Symptoms with any activity or even at rest. |
| B. World Health Organization functional assessment classification | |
| Class I: | Patients with PH but without resulting limitation of physical activity. Ordinary physical activity does not cause undue dyspnea or fatigue, chest pain, or near syncope. |
| Class II: | Patients with PH resulting in slight limitation of physical activity. They are comfortable at rest. Ordinary physical activity causes undue dyspnea or fatigue, chest pain, or near syncope. |
| Class III: | Patients with PH resulting in marked limitation of physical activity. They are comfortable at rest. Less than ordinary activity causes undue dyspnea or fatigue, chest pain, or near syncope. |
| Class IV: | Patients with PH with inability to carry out any physical activity without symptoms. These patients manifest signs of right-heart failure. Dyspnea and/or fatigue may even be present at rest. Discomfort is increased by any physical activity. |